Optical Coherence Tomography Angiography Examinations in Chronic Retinal Artery Occlusion
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 42
- 试验地点
- 1
- 主要终点
- Capillary density in relation to healthy subjects
研究概览
简要总结
Purpose of the study is to examine the retinal blood flow in chronic cases of retinal artery occlusion with non-invasive, non-contact optical coherence tomography angiography.
详细描述
Occlusion of the retinal arteries is an emergency which causes sudden, painless unilateral vision loss. Loss of blood flow causes ischemic damage to the retina. The extent of damage depends on the area affected.
Following the acute phase of the disease re-canalization occurs and lesser blood flow can be detected usually without functional recovery.
Purpose of the study is to examine the retinal blood flow in chronic cases of retinal artery occlusion.
Standard procedures to examine this disease include retinoscopy following pupil dilation, fluorescein angiography and more recently, optical coherence tomography (OCT).
The latest direction in OCT development was OCT angiography (OCTA) which is a software upgrade that allows detection of blood flow based on motion contrast. Similar to previous OCT machines OCTA is also non-invasive and non-contact and does not require any intravenous agents.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •central or branch retinal artery occlusion
- •at least 6 months of onset
- •signed informed consent
排除标准
- •known epilepsy
- •incapacity
- •presence of optical media opacities that would disturb the imaging
- •presence of other retinal diseases that would disturb the evaluation of images
结局指标
主要结局
Capillary density in relation to healthy subjects
时间窗: Through study completion, 1 year
次要结局
- Correlation of capillary density and retinal thickness(Through study completion, 1 year)
研究者
Miklos Schneider MD, PhD
Assistant Professor
Semmelweis University