The Difference of Lung Volume Change Detected by Electrical Impedance Tomography (EIT) Between Noninvasive Positive-pressure Ventilation (NIPPV) Support by Nasal Pillow and High Flow Nasal Cannula in Post-extubation Patients
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- • End-expiratory lung volume (EELV) determined by electrical impedance tomography after high flow nasal cannula and nasal pillow CPAP
研究概览
简要总结
The difference of lung volume change will be monitored by electrical impedance tomography before and after use of noninvasive positive pressure ventilation by nasal pillow and high flow nasal cannula in post-extubation patients.
详细描述
Electrical impedance tomography can effectively monitor the lung volume change in ICU patients who were under mechanical ventilator or noninvasive positive pressure ventilator support. Continuous positive airway pressure (CPAP) support by nasal pillow and high flow nasal cannula can improve inspiratory function in extubated patients . However, the extent of lung volume change or functional residual volume (FRC) change by using these two devices were never surveyed before in extubated patients. The investigators will check end-expiratory lung volume (EELV) ,anterior, medio-anterior, medio-posterior and posterior EELV by electrical impedance tomography after use of these two devices in extubated patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Any extubated patients after tolerating spontaneous breathing trial
排除标准
- •Presence of tracheostomy
- •Recent facial trauma
- •Active gastro-intestinal bleeding
- •Do-not-intubate status and
- •Planned use of BiPAP after extubation.
- •Patients with unstable spinal lesions or fractures.
- •Patients with a cardiac pacemaker
- •Burn injury with skin defect
研究组 & 干预措施
Nasal pillow CPAP
Nasal pillow CPAP
干预措施: Nasal Pillow CPAP (Device)
结局指标
主要结局
• End-expiratory lung volume (EELV) determined by electrical impedance tomography after high flow nasal cannula and nasal pillow CPAP
时间窗: at day 1
次要结局
- Anterior, medio-anterior, medio-posterior and posterior EELV at each time(at day 1)
