Non-Invasive Measurements of Changes in Pulmonary Artery Pressure in Intensive Care Unit Patients Using Electrical Impedance Tomography - A Feasibility Study (PAP-EIT Study)
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Mean difference between EIT-derived and PAC-measured changes in pulmonary artery pressure
研究概览
简要总结
To assess whether changes in electrical impedance - measured using an electrical impedance tomography (EIT) chest belt - can be used to derive changes in pulmonary artery pressure (PAP) in critically ill patients when compared to invasive gold-standard PAP measured using pulmonary artery catheter (PAC).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Mean difference between EIT-derived and PAC-measured changes in pulmonary artery pressure
时间窗: Up to 48 hours
The primary outcome is the difference - expressed as mean and standard deviation (SD) - between changes in EIT-derived pulmonary artery pressure (ΔPAP_EIT), derived from changes in the pulmonary pulse arrival time, and changes in pulmonary artery catheter-based pulmonary artery pressure (ΔPAP_PAC). This will be measured over recording periods of up to 48 hours.
次要结局
- Data acceptance rate(Up to 48 hours)
- Accuracy and trending ability of EIT-derived cardiac output compared to PAC measurements(Up to 48 hours)
- Concordance rate (%) of directional changes in pulmonary artery pressure between EIT and PAC measurements (Trending ability)(Up to 48 hours)
- Agreement between EIT-derived and ventilator-measured respiratory parameters(Up to 48 hours)