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Clinical Trials/NCT02292992
NCT02292992
Unknown
Not Applicable

The Difference of Lung Volume Change Detected by Electrical Impedance Tomography (EIT) Between Noninvasive Positive-pressure Ventilation (NIPPV) Support by Nasal Pillow and High Flow Nasal Cannula in Post-extubation Patients

Mackay Memorial Hospital1 site in 1 country40 target enrollmentDecember 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Respiratory Failure
Sponsor
Mackay Memorial Hospital
Enrollment
40
Locations
1
Primary Endpoint
• End-expiratory lung volume (EELV) determined by electrical impedance tomography after high flow nasal cannula and nasal pillow CPAP
Last Updated
11 years ago

Overview

Brief Summary

The difference of lung volume change will be monitored by electrical impedance tomography before and after use of noninvasive positive pressure ventilation by nasal pillow and high flow nasal cannula in post-extubation patients.

Detailed Description

Electrical impedance tomography can effectively monitor the lung volume change in ICU patients who were under mechanical ventilator or noninvasive positive pressure ventilator support. Continuous positive airway pressure (CPAP) support by nasal pillow and high flow nasal cannula can improve inspiratory function in extubated patients . However, the extent of lung volume change or functional residual volume (FRC) change by using these two devices were never surveyed before in extubated patients. The investigators will check end-expiratory lung volume (EELV) ,anterior, medio-anterior, medio-posterior and posterior EELV by electrical impedance tomography after use of these two devices in extubated patients.

Registry
clinicaltrials.gov
Start Date
December 2014
End Date
October 2015
Last Updated
11 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Any extubated patients after tolerating spontaneous breathing trial

Exclusion Criteria

  • Presence of tracheostomy
  • Recent facial trauma
  • Active gastro-intestinal bleeding
  • Do-not-intubate status and
  • Planned use of BiPAP after extubation.
  • Patients with unstable spinal lesions or fractures.
  • Patients with a cardiac pacemaker
  • Burn injury with skin defect

Outcomes

Primary Outcomes

• End-expiratory lung volume (EELV) determined by electrical impedance tomography after high flow nasal cannula and nasal pillow CPAP

Time Frame: at day 1

Secondary Outcomes

  • Anterior, medio-anterior, medio-posterior and posterior EELV at each time(at day 1)

Study Sites (1)

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