Effectiveness of Magnetic Stimulation of Brain in Treatment of Generalized Anxiety Disorder
- Conditions
- Health Condition 1: F411- Generalized anxiety disorder
- Registration Number
- CTRI/2024/01/061662
- Lead Sponsor
- Sri Guru Ram Rai Institute of Medical and Health Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Patient with a diagnosis of Generalized anxiety disorder based on diagnostic criteria of Diagnostic and Statistical Manual of mental disorder, fifth edition (DSM-5), or International Classification of Disease (ICD-11).
2.Patients aged between 18-59 years
3.Patients giving written consent to participate in protocol.
4.Right-handed, normotensive patient.
5.Severity of illness: HAM-A score >18 or Clinical Global Impression–Severity score of 4 or greater.
1.Patient is uncooperative for the procedure.
2.Patients with neurological disorders with history of epilepsy, organic brain damage or any neurological procedures.
3.Patients with mild to moderate depression (HAM-D score >13).
4.Patients with implanted metallic devices.
5. Patients receiving ECT in past 6 months.
6. Patients with other neurovascular comorbidities (tumor, cerebro-vascular events, cranio-encephalic trauma).
7. Significant unstable medical condition like uncontrolled hypertension, complicated diabetes mellitus or any organ failure.
8. Patients with psychotic disorders and substance use disorders, except nicotine and caffeine (as per DSM-5)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess and compare in the anxiety symptoms in patients suffering from Generalized Anxiety Disorder following continous theta burst stimulation in active and sham group.Timepoint: The patient will be assessed using HAM-A, CGI-S and WHOqol-BREF at baseline, 7th day and 21st day
- Secondary Outcome Measures
Name Time Method To assess illness severityTimepoint: CGI applied at Day0,7 and 21 days;To assess quality of lifeTimepoint: WHO-QOL applied at Day 0, 7 and 21 days