A study comparing Carbetocin and oxytocin for prevention of post partum hemorrhage following vaginal delivery
Not Applicable
- Conditions
- Health Condition 1: O80- Encounter for full-term uncomplicated deliveryHealth Condition 2: O80- Encounter for full-term uncomplicated delivery
- Registration Number
- CTRI/2024/04/065975
- Lead Sponsor
- Dr.Saranya,Postgraduate in Obstetrics and gynaecology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Pregnant women in age group 18-35 years
1. Singleton pregnancy
2. Term (37-42 weeks of gestation)
3. Women who undergo vaginal delivery
4. Patients willing to give informed consent
Exclusion Criteria
High risk pregnant women including: antepartum hemorrhage- placenta previa, abruptio
placentae, preeclampsia, eclampsia, GDM A2, multiple pregnancies, post cesarean
pregnancy, polyhydramnios, macrosomia, patients with gynecological disorders such as
myomas
? Medical disorders: coagulation disorders, thrombocytopenia (platelets <1.5 lakh), renal
disorders, hepatic disorders, heart disease, asthma, epilepsy, women with HIV
? Intellectual challenged women
? Known allergy to carbetocin
? Patients not willing to sign informed consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method terine tone and vaginal bleeding immediately and at 1, 2, 3 hours post delivery in both the <br/ ><br>groups <br/ ><br>1.Estimated blood loss (ml) and PPH (blood loss 500 ml) in both study groups <br/ ><br> <br/ ><br>2. Need for use of additional uterotonic drugs and/or blood transfusion in both the groupsTimepoint: 1-3 Days after Randomization <br/ ><br>
- Secondary Outcome Measures
Name Time Method Change in value of hemoglobin, Hematocrit and Packed cell volume (PCV)Pre and 24 -hour <br/ ><br>post-delivery in both the groups <br/ ><br> ? Drug related adverse effects such as nausea, vomiting, shivering, headache, anaphylaxis in <br/ ><br>both the groupsTimepoint: 1-3 Days after Randomization