NCT06506552已完成不适用
Inferior Mesenteric Artery Preservation in Laparoscopic Colorectal Resection for Diverticular Disease; Short and Long Term Effects in Defecatory Function
University of Roma La Sapienza0 个研究点目标入组 300 人开始时间: 2012年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 300
- 主要终点
- Defecatory disorders
研究概览
简要总结
This is a prospective randomized study aimed to verifying the short and long-term results of inferior mesenteric artery preservation following colorectal resection for diverticular disease
详细描述
This study wants to demonstrate that the preservation of the inferior mesenteric artery allow to improve postoperative defecatory function and improve patient's quality of life.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •BMI < 35
- •ASA I-III
- •Hinchey I-III
排除标准
- •BMI > 35
- •Hinchey IV
- •Previous procedures that could have been modified the nervous mesenteric pattern (surgery, radiotherapy or chemotherapy)
结局指标
主要结局
Defecatory disorders
时间窗: 6 years from surgery
the presence of defecatory disorders was evaluated (Costipation, Evacuation frequency,evacuation urgency, fragmented evacuation,flatus incontinence, liquid incontinence)
次要结局
- Postoperative surgical complication(1 month from surgery)
- Constipation(6 years from surgery)
- Incontinence(6 years from surgery)
- Anorectal Muscles function(6 years from surgery)
- Postoperative quality of life(6 years from surgery)
研究者
Francesco Saverio Mari, MD, PhD, FACS
Research fellow
University of Roma La Sapienza
相似试验
已完成
不适用
Preservation of Inferior Mesenteric Artery Could Improve Sexual Function After Laparoscopic Colorectal Resection for Diverticular DiseaseSexual Function DisturbancesNCT04752241University of Roma La Sapienza300
Unknown
不适用
Comparison of Laparoscopic Versus Open Gastrectomy for Advanced Gastric Cancer:A Prospective Randomized TrialStomach NeoplasmLaparoscopyGastrectomyComplicationsNCT01043835Yan Shi328
终止
不适用
Laparoscopic or Conventional Mesh Repair of Incisional and Umbilical HerniaIncisional HerniaUmbilical HerniaNCT00970515Assistance Publique - Hôpitaux de Paris98
已完成
3 期
Improvement of Anorectal Function While Preserving of Inferior Mesenteric Artery Performing Left Hemicolectomy for DiverticulosisDefecatory Disorders After Left Colonic or Rectal ResectionNCT01326052University of Roma La Sapienza150
已完成
不适用
Clinical Trial Comparing Open and Laparoscopic Nissen Fundoplication in ChildrenGastroesophageal RefluxNCT00382850Johns Hopkins University68