Hemodynamic characterization in hypertrophic cardiomyopathy after septal myectomy +/- mitral valve repair: a 4D-flow MRI study

Recruiting

• Conditions: Hypertrophic cardiomyopathy; 10028593

• Registration Number: NL-OMON50330
• Lead Sponsor: Amsterdam UMC

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Patients that underwent septal myectomy +/- mitral valve repair due to
hypertrophic cardiomyopathy

Exclusion Criteria

- Have underwent a cardiac reoperation after the initial surgical myectomy +/-
MVR procedure
- Have major comorbidity besides HCM
- Are under the age of 18.
- Have claustrophobia or another contra-indication for MRI.
- Are not able to provide written informed consent.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are;<br /><br>- blood flow velocity<br /><br>- wall shear stress and energy loss over the aortic valve, the ascending<br /><br>aorta, the aortic arch and descending aorta</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Routine MRI parameters;<br /><br>- enddiastolic and endsystolic volumes<br /><br>- stroke volume<br /><br>- ejection fraction</p><br>