Hemodynamic characterization of cardiac disease and aortopathy in congenital heart disease: a 4D flow MRI study

Completed

• Conditions: congenital heart disease; 10007510

• Registration Number: NL-OMON46219
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 180

Inclusion Criteria

Patients with bicuspid aortic valve disease, coarctation of the aorta, patients with fontan circulation or patients with aortic dilatation

Exclusion Criteria

A subject is excluded from participation in the study when meeting the following criteria:;- Unable to provide informed consent.
- Metal objects inside the body.
- Pregnant women.
- Claustrophobia.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>BAV patients<br /><br>Shear stress in the ascending aorta<br /><br>Energyloss near the aortic valve.<br /><br>Flow patterns in the ascending aorta<br /><br><br /><br>CoA patients<br /><br>Shear stress in the ascending aorta, CoA repair site, and descending aorta.<br /><br>Energyloss near the CoA repair site.<br /><br>Flow patterns in the aorta ascendens<br /><br><br /><br>Fontan patients<br /><br>Eenergy loss in the cavo-pulmonal circulation<br /><br><br /><br>Aortic dilatation<br /><br>Shear stress in the ascending aorta<br /><br>Flow patterns in the ascending aorta</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>N/A</p><br>