Hemodynamic characterization of cardiac disease and aortopathy after valve sparing aortic root replacement, mechanical aortic valve implantation or septal myectomy: a 4D-flow MRI study

Completed

• Conditions: prosthetic heart valve; valve sparing aortic replacement; 10046973

• Registration Number: NL-OMON43202
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Trial ended prematurely

Detailed Description

Not available

Study Timeline

• Study Completion: 2020-01-01
• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 44

Inclusion Criteria

Adult patients who had a valve sparing aortic root replacement by a David or Yacoub procedure, a mechanical aortic valve implantation or a septal myectomy due to hypertrophic cardiomyopathy

Exclusion Criteria

Contra-indications for MRI(see protocol for specification)
Cardiac surgery less than six months ago

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>blood flow velocity and patterns, flow turbulence, wall shear stress and energy<br /><br>loss </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable </p><br>