Acute and Chronic Effects of Low-Intensity Blood Flow Restriction Training in Normoxia and Hypoxia Conditions on Muscle Strength, Thickness, Catecholamine, and Inflammatory Responses in Physically Active Adults
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Countermovement Jump Height
研究概览
简要总结
One approach to significantly reducing resistance training intensity while maintaining effectiveness in muscle mass and strength development involves conducting training sessions under hypoxic conditions. This is likely due to heightened physiological responses. While sports science research indicates a substantial impact of hypoxic conditions on immediate increases in metabolic stress and augmented hormonal responses, recent findings suggest that the role of their influence on skeletal muscle adaptations post-resistance training under hypoxic conditions remains unknown. Additionally, there is a lack of reports on whether the type of hypoxia applied via blood flow restriction or chamber differentiates the increase in secretion of these catecholamines in both immediate and long-term aspects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Regularly physically active (at least 30 mins of structured exercise 3 times per week),
- •Sea-level natives,
- •Experienced in resistance training (at least one year of experience in regular resistance exercise)
排除标准
- •presence of any medical risk factors to exercise and/or exposure to altitude
- •presence of any medical condition that would make the protocol unreasonably hazardous for the participant
结局指标
主要结局
Countermovement Jump Height
时间窗: Immediately pre and post first and last training session
Countermovement jump height will be performed estimated via take-off velocity performed on force plates to Participants will perform 3 trials on force plate.
Catecholamine Response
时间窗: Immediately pre and post first and last training session
A blood sample will be analyzed to quantify changes in epinephrine and norepinephrine level changes.
Force Output
时间窗: Immediately pre and post first and last training session
Force plate will be used to quantify maximum absolute (N) and relative force output (body mass divided per force output in N/kg) during maximum voluntary isometric back squat in a 100ms time frame. Participants will be pushing as hard and as fast as they can on an unmoveable barbell while standing on a force plate.
One-Repetition Maximum
时间窗: within 5 days from the start and end of training
One-Repetition Maximum test in leg press exercise will be performed to quantify maximum lower body dynamic strength (kg). Participants will be performing single repetitions of leg press exercise with increasing load until volitional failure.
Countermovement Jump Power Output
时间窗: Immediately pre and post first and last training session
Countermovement jump performance will be performed to quantify maximum lower body relative and absolute power-output (W/kg and W), and jump height (cm) with concomitant assessment of contraction depth (cm) and contraction time (ms). Participants will perform 3 trials on force plate.
Maximum Number of Repetitions
时间窗: within 5 days from the start and end of training
A maximum number of repetitions in leg press exercise will be performed to quantify lower body strength endurance (number). Participants will be performing leg press exercise at 50% of one-repetition maximum until volitional failure.
Muscle Thickness
时间窗: within 5 days from the start and end of training
Ultrasonography measure will be used to quantify changes in vastus medialis oblique cross-sectional area.
Muscle Stiffness
时间窗: Immediately pre and post first and last training session
Myotonometry measure will be used to quantify changes in vastus medialis oblique muscle stiffness in N/m
次要结局
- Perception of Pain(Immediately pre and post every training session)
- Perception of Effort(Immediately pre and post every training session)
- Blood Pressure(Immediately pre and post first and last training session)
研究者
Michal Krzysztofik
Associate Professor
The Jerzy Kukuczka Academy of Physical Education in Katowice