Application and histologic evaluation of hyaluronic acid in the treatment of gingival papilla loss

Not Applicable

Completed

• Conditions: Treatment of gingival papilla loss for patients diagnosed with periodontal disease; Oral Health

• Registration Number: ISRCTN12070271
• Lead Sponsor: Victor Babe? University of Medicine and Pharmacy Timi?oara

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2024-04-01
• Study Start: 2024-04-25
• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

1. Nonsmoking, aged above 18 years
2. Presence of an uninterrupted frontal arch (maxillary or mandibular) of teeth affected by severe periodontitis
3. Presence of interproximal pockets deeper than 6 mm in at least 6 adjacent teeth
4. Class I, II, or III papillary recession, according to Nordland and Tarnow's classification (1998)
5. The distance from the contact point to the alveolar bone crest =5 mm
6. Keratinized tissue width of the entire area to be operated of at least 3 mm
7. Good oral hygiene - Plaque Index (PlI<1)

Exclusion Criteria

1. Systemic diseases such as diabetes mellitus, hypertension, or conditions that alter the outcome of periodontal therapy
2. Pregnant or lactating women
3. Tobacco users
4. Patients with known allergies to hyaluronic acid or any excipients of the product used
5. Patients with current or previous drug intake that may predispose to gingival enlargement
6. Patients under orthodontic treatment or having orthodontic treatment in the past 6 months
7. Patients with a history of traumatic oral hygiene measures or periodontal surgeries over the last 6 months in the area of interest

Study & Design

• Study Type: Interventional
• Study Design: Not specified