Acute effects of different test meals on postprandial metabolism in elderly men and women with a risk phenotype for cardiovascular diseases

Not Applicable

Completed

• Conditions: postprandial metabolism

• Registration Number: DRKS00009861
• Lead Sponsor: niversität BonnIEL Ernährungsphysiologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-01-22
• Study Completion: 2016-07-05
• Last Update Posted: 2024-08-19

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Non smoking, Overweight/obesity (BMI 27-34,9 kg/m2), Visceral adiposity, Dyslipidemia, Pro-inflammatory state , Raised blood glucose, Prehypertension or stage 1 hypertension

Exclusion Criteria

Malabsorption syndromes, unmedicated thyroidal diseases, impaired function of the kidney, secondary hypertension, chronic liver-diseases, heart insufficiency, Prior myocardial infarction, insulin treated Diabetes Mellitus, untreated Diabetes insipidus, chronic inflammatory diseases including rheumatoid arthritis, presence of any tumors, chronic intake of nutrient-supplements, alcoholic abuse, medical abuse, immune suppression

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Parameter of endothelial function, inflammation, oxidation and lipid and glucose metabolism; <br>Fasting and postprandial hourly measurements for five hours<br>

Secondary Outcome Measures

Name	Time	Method
blood pressure (fasting, postprandial), determining apolipoprotein E (apoE) genotype and its effect of on primary study variables, plasma concentrations of neurofilament light (nfl) and tau protein, metabolomics analyses<br><br>