Use of Peroperative Antibiotics in Patients Undergoing Surgery For Breast Cancer

Completed

Conditions: Patients with proven diagnosis of carcinoma breast planned for modified radical mastectomy as decided by institute tumor board

Brief Summary: | |

| --- |

|Surgical site infection (SSI) is a major source of adverse operation-related event in patients undergoing surgery, including increased morbidity, additional cost and delay of postoperative adjuvant therapies. Till date no single study has been done exclusively defining the role of antibiotic prophylaxis in patients undergoing modified radical mastectomy (MRM) in India.The aim of this randomized clinical trial is to determine whether prophylactic antibiotics are indicated in patients undergoing MRM and to identify the risk factors that increase the rate of post operative SSI.

Recruitment & Eligibility

Inclusion Criteria

PATIENTS WHO ARE DIAGNOSED CASES OF CARCINOMA BREAST WHO ARE PLANNED TO UNDERGO MODIFIED RADICAL MASTECTOMY AS DECIDED BY THE INSTITUTE TUMOR BOARD.

Exclusion Criteria

Exclusion criteria 1.
Hypersensitivity to intravenous Cefazolin 2.Patients receiving antibiotics for some other reason 3.Patients with local skin infections at the site of surgery 4.Patients on steroids 5.Immunosuppressive disease(HIV).

Primary Outcome Measures

Name	Time	Method
Rate of Surgical Site Infection according to CDC definition	30 Days

Secondary Outcome Measures

Name	Time	Method
Detecting potential risk factors in the development of surgical site infection	30 Days

Locations (1): ward 34,37,Department Of General Surgery ,
🇮🇳
Pondicherry, PONDICHERRY, India
ward 34,37,Department Of General Surgery ,
🇮🇳Pondicherry, PONDICHERRY, India
Galidevara Indira
Principal investigator
9500990403
g.indira.surg@gmail.com