A pilot study to compare pharmacognostical, phytochemical, and therapeutic effect of Brihat Agnimantha (Premna integrifolia) and Laghu Agnimantha (Clerodendrum phlomidis) mool kwath in the management of Sthaulya (obesity).
Trial Snapshot
- Phase
- Phase 2/3
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Reduction in the sign and symptoms of Sthaulya(Obesity).
Study Overview
Brief Summary
The study presented focuses on the pharmacognostical, sephytochemical, and therapeutic aspects of two species of Agnimanth Brihat Agnimanth Premna integrifolia and Laghu Agnimanth Clerodendrum phlomidis in the context of treating Sthaulya obesity in Ayurveda
Pharmacognostical Study This involves the identification and standardization of Agnimanth species, crucial for authentication and prevention of adulteration. Initial research highlighted variations in pharmacognostical characteristics and phytochemical profiles between the two species.
Phytochemical Study Evaluating the constituents of Agnimanth species and their decoctions Kwath is essential to understand their bioactive components and therapeutic potential. Such studies aim to establish similarities or differences in formulations derived from these species.
Therapeutic Study Ayurvedic texts like Charak Samhita advocate Agnimanth as a treatment for Sthaulya, emphasizing its role in balancing doshas and improving Jatharagni to manage pathological increases in appetite. Modern research underscores the need to identify the most effective Agnimanth species for obesity management.
The need for pharmacognostical and phytochemical studies precedes therapeutic investigations, ensuring the identification and standardization of plant materials. This foundational work is essential for validating Ayurvedic treatments and developing effective herbal formulations.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- None
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •1.Patient having Clinical sign & symptom of Sthaulya as per Ayurvedic text. 2.Patient either sex between the Age group of
- •60year . 3.Patient having BMI more than or equal to 25kg/m2.
Exclusion Criteria
- •1.Patient below the age of 18 years and above 60 years 2.Patient of any chronic diseases 3.Pregnant and lactating women 4.Discontinuation criteria Any Acute or Severe Illness.
- •Patient not willing to continue the treatment.
Outcomes
Primary Outcomes
Reduction in the sign and symptoms of Sthaulya(Obesity).
Time Frame: After treatment of 60 days
Secondary Outcomes
- Changes in the subjective parameters.(after treatment period of 60 days.)
Investigators
Dr Rakesh Kumar
Institue for Ayurved studies and Research