Effect of hypertonic serum in patients with hemorrhagic shock

Not Applicable

Recruiting

• Conditions: hemorrhagic shock.; Hemorrhage, not elsewhere classified

• Registration Number: IRCT20230521058246N1
• Lead Sponsor: Bandare-abbas University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 16 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 440

Inclusion Criteria

People with hemorrhagic trauma confirmed by a physician
18 years or older people
In people exposed to penetrating or blunt trauma one hour before randomization
In people with systolic blood pressure =100 mm Hg
In people with informed consent regarding participation in the research
In people with a decrease in blood volume (more than 1000 ml)

Exclusion Criteria

Patients with a history of high blood chloride
Patients with a history of high sodium levels in the blood
Patients with a history of high potassium levels in the blood
Patients with a history of kidney dysfunction
Patients with a history of pregnancy
Patients with a history of epilepsy
Patients with a history of blood coagulation-related diseases
Patients with a history of liver disease
Patients with a history of a severe decrease in body temperature to less than 28 degrees Celsius
Patients with a history of inability to receive IV
Patients with a history of absence of cardiac sinus rhythm
Patients with a history of cardiac arrest
Patients with a history of cardiopulmonary resuscitation
Patients with a history of burns of more than 20% of the body surface
Patients with a history of increased intracranial pressure
Patients with a history of anaphylactic reactions
Patients with tissue or cellular dehydration
Patients with a history of receiving more than 2 liters of crystalloid before the study began
Patients with a history of suffocation caused by hanging
Patients transferred from other hospitals
Patients with excessive delay in the treatment process

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome of this study include a decrease in the mortality rate of patients due to hemorrhagic shock during the intervention period. Timepoint: Upon discharge. Method of measurement: Patient's File.

Secondary Outcome Measures

Name	Time	Method
Reducing the length of hospital stay. Timepoint: Upon discharge. Method of measurement: Patient's File.;Reducing the length of ICU stay. Timepoint: Upon discharge. Method of measurement: Patient's File.;Reducing the volume of blood and fluids received. Timepoint: After intervention. Method of measurement: Check list and patient's file.