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Clinical Trials/NCT05688150
NCT05688150
Completed
Not Applicable

Prevalence and Associated Factors of Sarcopenia Among Elderly Patients in Osteoporosis Clinic

Kowloon Hospital, Hong Kong1 site in 1 country94 target enrollmentJune 20, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sarcopenia
Sponsor
Kowloon Hospital, Hong Kong
Enrollment
94
Locations
1
Primary Endpoint
Prevalence of Sarcopenia
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

This was a cross-sectional study. Patients who attended the osteoporosis clinic of Kowloon Hospital from June to December 2022 were recruited.

Grip strength and appendicular skeletal muscle mass index were measured with a Jamar dynamometer and a bioimpedance analyser. Since most patients in our clinic are of Chinese ethnicity, the diagnostic criteria in the Consensus Update on Sarcopenia Diagnosis and Treatment by the Asian Working Group for Sarcopenia in 2019 was utilised. The diagnosis of sarcopenia was established by the presence of both low grip strength (Male: < 28 kg, Female < 18 kg) and low appendicular skeletal mass (Male: < 7.0 kg/m2, Female: < 5.7 kg/m2)

Registry
clinicaltrials.gov
Start Date
June 20, 2022
End Date
February 28, 2023
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Kowloon Hospital, Hong Kong
Responsible Party
Principal Investigator
Principal Investigator

Leung Hin Cheung

Principal Investigator

Kowloon Hospital, Hong Kong

Eligibility Criteria

Inclusion Criteria

  • Patients aged 60 years old or above
  • Diagnosed with osteoporosis by: Fragility fracture or T-score ≤-2.5 SDs at any site on DXA scan and;
  • Able to read and write Chinese

Exclusion Criteria

  • Unable to maintain standing posture for bioimpedance analysis
  • Modified Functional Ambulation Classification (MFAC) ≤ IV
  • Incompetent in giving consent
  • Unable to follow instructions
  • Implanted with metal in any of four limbs
  • Implanted with pacemaker, implantable cardioverter defibrillator or any other types of electrical device

Outcomes

Primary Outcomes

Prevalence of Sarcopenia

Time Frame: June - December 2022

The diagnosis of sarcopenia would be established by the co-existence of low grip strength and low appendicular skeletal muscle mass.

Grip strength

Time Frame: June - December 2022

Grip strength would be measured with Jamar digital dynamometer.

Appendicular Skeletal Muscle Mass Index

Time Frame: June - December 2022

Appendicular Skeletal Muscle Mass Index would be measured with bioimpedance analyzer.

Secondary Outcomes

  • Association between BMI and Sarcopenia.(June - December 2022)
  • Association between Frailty and Sarcopenia.(June - December 2022)
  • Association between Bone Mineral Densities and Sarcopenia(June - December 2022)
  • Association between Charlson Comorbidities Index and Sarcopenia(June - December 2022)

Study Sites (1)

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