Comparison of Two Laser Therapy Methods for PDR
Phase 2
- Conditions
- Proiriftrative Diabetic Retinopathy
- Interventions
- Procedure: conventional prpProcedure: targeted prp
- Registration Number
- NCT01232179
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Proliferative diabetic retinopathy (PDR) is treated with conventional pan retinal photocoagulation (PRP) which can improve the visual prognosis in this complication significantly. However , the treatment may also resulting adverse effects such as blurring of central vision, visual field constriction and disturbance in dark adaptation and contrast vision. Extended targeted retinal coagulation (TRP) to the ischemic areas may cause regression of the neovascularization while minimizing some of the risks and complication associated of treatment of PDR with these two methods.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- patients with PDR condidate for photocoagulation teraphy
- Pupil with dilatasion≥6mm
- without privious treatment with anti VEGF drugs 3months before study
- without privious vitroretinal sugery
- without privoius lasertraphy
Exclusion Criteria
- To have NVI cricteria with increase of inraocular pressure
- to have cataract or vitrus leakage which prevent lasertraphy
- pupil smaller that 6mm
- traditional retinal detachment
- privious treatment with anti VEGF drugs 3months before study
- privious PRP
- patient unable to get wide field FAG
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description conventional prp conventional prp - targeted PRP targeted prp -
- Primary Outcome Measures
Name Time Method no leakage in widefield fluorescin angiography 3 months after lasertraphy
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Labbafinejad medical center
🇮🇷Tehran, Iran, Islamic Republic of