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临床试验/NCT01232179
NCT01232179Unknown2 期

Comparison Between Result and Side Effects of Treatment of Prolifrative Diabetic Retinopaty by Conventional and Extended Targeted Pan Retinal Photocoagolation

Shahid Beheshti University of Medical Sciences1 个研究点 分布在 1 个国家开始时间: 2010年10月最近更新:
适应症

试验速览

阶段
2 期
试验地点
1
主要终点
no leakage in widefield fluorescin angiography

研究概览

简要总结

Proliferative diabetic retinopathy (PDR) is treated with conventional pan retinal photocoagulation (PRP) which can improve the visual prognosis in this complication significantly. However , the treatment may also resulting adverse effects such as blurring of central vision, visual field constriction and disturbance in dark adaptation and contrast vision. Extended targeted retinal coagulation (TRP) to the ischemic areas may cause regression of the neovascularization while minimizing some of the risks and complication associated of treatment of PDR with these two methods.

研究设计

研究类型
Interventional
分配方式
Randomized
主要目的
Treatment
盲法
Double (Participant, Investigator)

入排标准

性别
All
接受健康志愿者

入选标准

  • patients with PDR condidate for photocoagulation teraphy
  • Pupil with dilatasion≥6mm
  • without privious treatment with anti VEGF drugs 3months before study
  • without privious vitroretinal sugery
  • without privoius lasertraphy

排除标准

  • To have NVI cricteria with increase of inraocular pressure
  • to have cataract or vitrus leakage which prevent lasertraphy
  • pupil smaller that 6mm
  • traditional retinal detachment
  • privious treatment with anti VEGF drugs 3months before study
  • privious PRP
  • patient unable to get wide field FAG

结局指标

主要结局

no leakage in widefield fluorescin angiography

时间窗: 3 months after lasertraphy

次要结局

未报告次要终点

研究者

研究点 (1)

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