TDCS Effects on Motor Learning and Motor Control in Healthy Subjetcs

Not Applicable

Completed

• Conditions: Healthy

• Registration Number: NCT03931512
• Lead Sponsor: Centro Universitario La Salle

Brief Summary

Clinical Trial with two groups, transcranial direct current stimulation aplication and sham; triple blinded. The protocol is applied 5 consecutive days during the training of a manual dexterity task. Manual dexterity and somatosensory variables are measured pre intervention, post one day of intervention, post 5 days of intervention, and 5 days after finish the intervention.

Detailed Description

Clinical Trial with two groups, transcranial direct current stimulation aplication (1 mA ) and sham (ramp up and down of 30 seconds in total) . Bouth interventions will last 20 minutes; at the same time of the aplication bouth are going to train the manual dexterity with Purdue Pegboard Test.

This protocol is applied 5 consecutive days, also it have a follow up of 5 days more.

It is triple blinded. Manual dexterity and somatosensory variables are measured pre intervention, post one day of intervention, post 5 days of intervention, and 5 days after finish the intervention.

Study Timeline

• Study First Submitted: 2019-04-08
• Study First Submitted QC: 2019-04-25
• Study Start: 2019-04-30
• Study First Posted: 2019-04-30
• Primary Completion: 2019-06-01
• Study Completion: 2019-06-01
• Status Verified: 2022-06
• Last Update Submitted: 2022-06-22
• Last Update Posted: 2022-06-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 33

Inclusion Criteria

• healthy volunteers

Exclusion Criteria

• metal or skin lesions on the head
• brain stimulation in the last 6 months
• family history of epilepsy or seizures
• pacemaker or any cardiac involvement
• inability to understand or execute the task
• taking drugs that may influence cognition
• pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change in trained manual dexterity of the dominant hand	pre intervention, post one day of intervention, post 5 days of intervention, 5 days after finish the intervention	One hand manual dexterity is measured with Perdue Pegboard test

Secondary Outcome Measures

Name	Time	Method
Sleep Quality	5 days after finish the intervention	Pittsburgh Sleep Quality Index
Changes in two points discrimination	pre intervention, post one day of intervention, post 5 days of intervention, 5 days after finish the intervention	Two points discrimination is measured with an esthesiometer
Changes in trained manual dexterity of bouth hands	pre intervention, post one day of intervention, post 5 days of intervention, 5 days after finish the intervention	Two hands dexterity is measured with Perdue Pegboard test
Changes in maximal isometric hand grip force	pre intervention, post one day of intervention, post 5 days of intervention, 5 days after finish the intervention	Hand grip force is measured with Jamar dinamometer
Physical activity	5 days after finish the intervention	Long form of the International Physical Activity Questionnaire
Changes in nontrained manual dexterity of bouth hands	pre intervention, post one day of intervention, post 5 days of intervention, 5 days after finish the intervention	Two hands dexterity is mesured with Minesota Test
Changes in pain detection treshold	pre intervention, post one day of intervention, post 5 days of intervention, 5 days after finish the intervention	The pain detection treshold is measured with an algometer
Changes in nontrained manual dexterity of the dominant hand	pre intervention, post one day of intervention, post 5 days of intervention, 5 days after finish the intervention	One hand dexterity is mesured with Minesota Test
Changes in pressure detection treshold	pre intervention, post one day of intervention, post 5 days of intervention, 5 days after finish the intervention	The pressure detection treshold is measured with an algometer

Trial Locations

Locations (1)

CEULaSalle; 🇪🇸 Madrid, Spain