Comparison of the Efficacy of Intradermal injected Tranexamic Acid vs Hydroquinone cream in the Treatment of Melasma

Phase 2

• Conditions: Chloasma; Melasma.

• Registration Number: IRCT20180203038599N1
• Lead Sponsor: Ahvaz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 30 April 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

Women at the range of 18 to 50 years old
with symmetrical bilateral melasma
who signature the letter of satisfaction

Exclusion Criteria

Pregnant and lactating women
Oral contraceptive pill consumption in 12 months ago during RCT
History of coagulopathy and thrombotic disorder
Anticoagulant and antiepileptic drug consumption
Sensitivity to tranexamic acid
History of treatment for melasma during 1 month ago
Active facial herpes simplex virus infection
Facial wart
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Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Melasma area and severity index. Timepoint: Melasma area and severity index measured at base of trial and 4, 8, 12 and 22. Method of measurement: Melasma area and severity index score.

Secondary Outcome Measures

Name	Time	Method
Patients satisfaction. Timepoint: Measuring of patient satisfaction in 8, 12 and 22 week of trial. Method of measurement: Satisfaction percentage questionnaire.