Effect of Ascorbic acid in treatment of melasma

Phase 3

Recruiting

• Conditions: Melasma.; Chloasma; L81.1

• Registration Number: IRCT20191213045719N1
• Lead Sponsor: Ahvaz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 February 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 24

Inclusion Criteria

Women at the range of 18 to 50 years old
patients with symmetrical bilateral melasma

Exclusion Criteria

Patient who is pregnant or in lactation period
Patient who had taken oral contraceptive pill in 12 months ago
Patient who has history of coagulopathy and thrombotic disorder
Patient who ia taking anticoagulant and antiepileptic drug
Patient who has sensitivity to tranexamic acid
Patient who has history of treatment for melasma during 1 month ago
Patient who has active facial herpes simplex virus infection
Patient who has facial wart

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Melasma area and severity index. Timepoint: Melasma area and severity index measured at base of trial and 4, 8, 12 and24 weeks of trial. Method of measurement: Melasma area and severity index.

Secondary Outcome Measures

Name	Time	Method
Patient satisfaction. Timepoint: Measuring of patient satisfaction in 4, 8, 12 and 24 weeks of trial. Method of measurement: Satisfaction percentage questionnaire.