Specificity of the saliva cortisol measurements in patients with obesity and development of a weight-dependent threshold value for the saliva cortisol for obese patients with a BMI > 35 for better early detection of Cushingsyndroms
Recruiting
- Conditions
- E66E24ObesityCushing syndrome
- Registration Number
- DRKS00006826
- Lead Sponsor
- ovartis GmbH
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 367
Inclusion Criteria
1. Age : 18-60 years ( and the capacity to consent )
2. Patients with grade III obesity i.e . BMI = 35 kg / m²
Exclusion Criteria
1. pregnancy
2. Current or recent previous history of use of cortisone preparations ( inhalants , topical , tablets, injections)
3. Shift work
4. Acute infection
5. Severe hepatic and renal insufficiency and heart failure
6. chewing tobacco consume
7. taking phenytoin, barbiturates , loperamide, opioids
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br><br><br><br>Investigation of the specificity and (sensitivity ) of salivary cortisol measurement in obesity patients to determine a weight specific cortisol level<br>
- Secondary Outcome Measures
Name Time Method