effect of VitD3 on Kidney and Muscle in Sepsis
Phase 2
- Conditions
- sepsis.
- Registration Number
- IRCT20150621022852N3
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Critically ill patients within 24 hours of new-onset sepsis
Had three out out of four criteria used to explain the systemic inflammatory response syndrome
Were expected to stay in the ICU for at least 48 hours
Exclusion Criteria
Acute Kidney Injury
At least two risk factors for AKI
Rapidly changing GFR
Rapidly changing serum creatinine
Rapidly changing cystatin C
Pregnancy
History of organ transplantation
Hypercalcemic (ionized calcium>1.3 mmol/L)
Maintenance renal replacement therapy
Platelets <30,000 per mm3 (Coagulopathy)
International normalized ratio > 3 (Coagulopathy)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sarcopenic index. Timepoint: before the intervention, 14, 21 days after intervention. Method of measurement: serum creatinine-to-serum cystatin C ratio ×100.
- Secondary Outcome Measures
Name Time Method