Proactive treatment of collateral ventilation in CV-positive emphysema patients before EBV treatment
Recruiting
- Conditions
- Chronic Obstructive Pulmonary DiseaseEmphysema
- Registration Number
- NL-OMON23885
- Lead Sponsor
- Investigator initiated study, Univeristy Medical Center Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
1.Diagnosis of upper or lower lobe heterogeneous emphysema with a difference in heterogeneity of ¡Ý 25% in destruction at -950HU between ipsilateral lobes.
2.Subjects of both genders of at least 35 years of age at the time of the baseline visit.
Exclusion Criteria
1.Evidence of active pulmonary infection.
2.Evidence of clinically significant bronchiectasis.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Feasibility: Evidence of targeted lung volume reduction (TLVR) on CT scan at 1 month Follow Up.
- Secondary Outcome Measures
Name Time Method Safety: The number and type of procedure-related (serious) adverse events within 3 months after the procedure.<br /><br><br /><br>Effectiveness: Change in TLVR, lung function, exercise capacity and quality of life at 3 months Follow Up.<br>