Central Corneal Thickness in Patients With Exfoliation Syndrome, Exfoliative Glaucoma, Exfoliative Glaucoma, Primary Open-angle Glaucoma and Ocular Hypertension
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 700
- 试验地点
- 1
- 主要终点
- central corneal thickness
研究概览
简要总结
The purpose of this study is to compare the central corneal thickness measurement in patients with exfoliation syndrome, exfoliative glaucoma, primary open-angle glaucoma, ocular hypertension and normal controls and to evaluate the value of corneal thickness in the diagnosis and management of glaucoma.
详细描述
To compare the central corneal thickness measurement in patients with exfoliation, primary open-angle glaucoma, ocular hypertension and normal controls and to evaluate the value of corneal thickness in the diagnosis and management of glaucoma. Prospective study in progress. Randomly selected patients undergo a comprehensive ophthalmic exam which includes 2 separate pachymetry measurements in 2 different examinations at the same time of the day (10:00 am) with 3 different pachymeters. The values obtained are correlated with a number of other glaucoma parameters. A thinner cornea may represent a specific attribute and an additional risk factor for patients with exfoliation. Evaluation of corneal thickness is an important exam in the management of patients with exfoliation.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 25 Years 至 89 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Exfoliation material on pupil
- •Intraocular pressure below 21 mm Hg without glaucomatous damage
- •Intraocular pressure above 21 mm Hg without glaucomatous damage
- •Raised intraocular pressure with glaucomatous damage
排除标准
- •Corneal disorders
- •History of trauma
- •Evidence of corneal abnormality that may influence IOP
- •Contact lens use
- •Corneal surgery
结局指标
主要结局
central corneal thickness
时间窗: Morning measurement (10:00-11:00)
次要结局
- Visual field, scanning laser polarimetry(10:00-11:00)
研究者
AGP Konstas
Professor in Ophthalmology
Aristotle University Of Thessaloniki