Effect of clearing the secretions below the entry of windpipe( Trachea) in prevention of lung infection associated with breathing machine.

Not yet recruiting

• Conditions: Patients who are admitted in the surgical Intensive Care unit

• Registration Number: CTRI/2017/11/010587

Brief Summary

Recruited 172 subjects will be  randomised into two  groups- groupC who will receive regular endotracheal tube and group S who will receive endotracheal tube with a port for subglottic suctioning. The primary outcome is to note the incidence of ventilator associated pneumonia between the two groups. The objective measures noted for primary outcome are  : temperature, total count, secretions (clear/purulent),rales/bronchial breath sounds, inspired oxygen concentration (FiO2), PEEP, Chest X ray (infiltrate/consolidation) , microbiological analysis. These are recorded every day from Day 1 to Day14. The secondary outcome is duration of ventilation, duration of ICU stay, addition of new antibiotics and 30 day mortality. Data collected will be statistically analysed.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-04-12
• Last Update Posted: 2017-11-21

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 172

Inclusion Criteria

All patients aged between 18-70 years who are expected to be ventilated for a duration of more than 72 hours.

Exclusion Criteria

1.Patients with pneumonia, Acute respiratory distress syndrome 2.Patients suspected to have pulmonary aspiration 3.Intubated patients received from another hospital.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome will be the incidence of Ventilator Associated Pneumonia (VAP).	Everyday at 10 AM from Day 1 to Day 14 the objective parameters are assessed

Secondary Outcome Measures

Name	Time	Method
duration of ventilation, duration of ICU stay, addition of new antibiotics and 30 day mortality	Everyday at 10 AM from Day 1 to Day 30 the parameters are assessed

Trial Locations

Locations (1)

St. Johns medical college hospital; 🇮🇳 Bangalore, KARNATAKA, India

St. Johns medical college hospital

🇮🇳Bangalore, KARNATAKA, India

Dr Moses Charles DSouza

Principal investigator

7829000524

drmosescharlesdsouza@gmail.com