The Effect of Simulated Obstructive Apnoea and Hypopnoea on Heart Rhythm in Patients With Paroxysmal Atrial Fibrillation

Not Applicable

Completed

• Conditions: Patients With Paroxysmal Atrial Fibrillation

• Registration Number: NCT01796080
• Lead Sponsor: University of Zurich

Brief Summary

In this randomised controlled cross-over study we will investigate whether intrathoracic pressure changes induced by simulated obstructive apnoea and hypopnoea trigger premature supraventricular and ventricular contractions as well as atrial fibrillation in patients with paroxysmal atrial fibrillation.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-10
• Study First Submitted: 2013-02-18
• Study First Submitted QC: 2013-02-18
• Study First Posted: 2013-02-21
• Status Verified: 2013-12
• Primary Completion: 2013-12
• Study Completion: 2013-12
• Last Update Submitted: 2013-12-20
• Last Update Posted: 2013-12-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Number of subjects with premature myocardial contractions and/or atrial fibrillation	20 seconds

Secondary Outcome Measures

Name	Time	Method
ECG-derived myocardial de- and repolarization times	20 seconds

Trial Locations

Locations (1)

University Hospital Zurich, Division of Pneumology; 🇨🇭 Zurich, ZH, Switzerland