The Effect of Volume Controlled Versus Pressure Ventilation on Anesthesia Induced Lung Atelectasis in Pediatrics Using Laryngeal Mask Airway (LMA )During Cardiac Catheterization. A Prospective Randomized Study.
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Post operative incidence of Lung atelectasis immediate post-removal of LMA.
研究概览
简要总结
This prospective randomized comparative study, to assess post-operative lung atelectasis by comparing calculated lung score using ultrasound between pediatric patients intubated with LMA (laryngeal mask airway) under volume versus pressure controlled modes of ventilation.
详细描述
The initial US scanning will be done prior to the induction of anesthesia. Induction of anesthesia using 4% sevoflurane. Adequate size LMA will be inserted after adequate depth of anesthesia adjusted.
Group A (n=25): will receive pressure-controlled ventilation (PCV). Group B (n=25): will receive volume-controlled ventilation (VCV).
US scanning and Arterial blood gases at the following:
- T1(After maintenance of anesthesia).
- T2 (One minute after applying groin bandage and before extubation).
- T3 (10 minutes after extubation and resumption of adequate regular breathing).
- T4 (30 min post extubation).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Double (Participant, Outcomes Assessor)
盲法说明
Patients will be randomly allocated by a computer-generated list (www.randomization.com) into one of the study groups in the day of the study . The randomization sequence will be concealed in sealed envelopes and will be opened by an independent nurse. The data collector and data analysis will be blind to group assignments.
入排标准
- 年龄范围
- 2 Years 至 6 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Pediatric patients undergoing cardiac catheterization procedures. Age from 2 years to 6 years of both sexes.
排除标准
- •Lung score at different times.
- •Age <2 years and >6 years.
- •Preoperative mechanical ventilation.
- •Heart failure (any inotropic support infusion).
- •Patients with any lung diseases( acute respiratory disease, pulmonary or lung
- •diseases).
- •Lung consolidation score ≥ 2 before insertion of LMA.
- •Any contraindication for LMA insertion (risk for aspiration, and/or airway
- •obstruction below the larynx.)
- •Procedures exceeding 120 mins duration.
结局指标
主要结局
Post operative incidence of Lung atelectasis immediate post-removal of LMA.
时间窗: immediated post removal of LMA
calculate lung score using lung ultrasound
次要结局
- Correlation between lung score and PaO2 /FiO2 ratio(From the preoperative period (T0) to 30 minutes post-extubation)
研究者
Dalia Saad Abd-El Kader
assistant professor
Kasr El Aini Hospital