Branched Chain Amino Acid and Muscle mass in Chronic Liver Disease
Phase 1
- Conditions
- Health Condition 1: K746- Other and unspecified cirrhosis ofliver
- Registration Number
- CTRI/2020/05/025459
- Lead Sponsor
- Indian Council of Medical Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients with decompensated cirrhosis (CTP
7-9) of all etiologies
2. Age: 18-60yrs
3. Hemostatically stable patients with platelet
>80000
4. INR <1.5 or 1.5-2.5 â?? to be corrected with Vitamin K
5. Who give consent for muscle biopsy
6. BMI <23
Exclusion Criteria
1. Presence of overt hepatic encephalopathy
2. Patients with co-morbidities like acquired immunodeficiency syndrome, HCC, Other cancer, diabetes mellitus, chronic kidney disease, congestive heart disease, chronic respiratory disease
3. Patients continuing to take alcohol in past 3 months
4. Patients with transjuglar intrahepatic portosystemic shunt [TIPS]
5. Patients on steroids
6. INR >2.5
7. Refusal to participate in the trial
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method