Comparison of PET/CT vs. PET/MRI
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 53
- 试验地点
- 1
- 主要终点
- Absolute Accuracy of SUV Max of PET/CT vs PET/MRI
研究概览
简要总结
This clinical trial studies how well positron emission tomography (PET)/computed tomography (CT) works compared to PET/magnetic resonance imaging (MRI) in evaluating patients with cancer. PET/CT and PET/MRI may determine which scanner is best for the patient's type of cancer and other types of cancers.
详细描述
PRIMARY OBJECTIVES:
I. To evaluate if PET/CT and PET/MRI scanners provide equivalent results for evaluation of cancer patients.
OUTLINE:
Patients receive standard of care 18F-fludeoxyglucose (FDG) or Ga68-DOTA-TATE intravenously (IV). Within 45-60 minutes, patients then undergo PET/CT imaging immediately followed by PET/MRI. Each participant is to receive 18-FDG or 68Ga-DOTA-TATE only, no participant was to receive both radiotracers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
18F-FDG PET/MRI Scan
Participants will undergo a PET/MRI scan with radiolabel 18F-FDG.
干预措施: F-18 FDG (Drug)
18F-FDG PET/CT Scan
Participants will undergo a PET/CT scan with radiolabel 18F-FDG.
干预措施: F-18 FDG (Drug)
18F-FDG PET/CT Scan
Participants will undergo a PET/CT scan with radiolabel 18F-FDG.
干预措施: Positron Emission Tomography / Computed Tomography (PET/CT) Scan (Device)
18F-FDG PET/MRI Scan
Participants will undergo a PET/MRI scan with radiolabel 18F-FDG.
干预措施: Positron Emission Tomography / Magnetic Resonance Imaging (PET/MRI) Scan (Device)
68Ga-DOTA-TATE PET/CT Scan
Participants will undergo a PET/CT scan with radiolabel 68Ga-DOTA-TATE.
干预措施: Ga-68-DOTA-TATE (Drug)
68Ga-DOTA-TATE PET/CT Scan
Participants will undergo a PET/CT scan with radiolabel 68Ga-DOTA-TATE.
干预措施: Positron Emission Tomography / Computed Tomography (PET/CT) Scan (Device)
68Ga-DOTA-TATE PET/MRI Scan
Participants will undergo a PET/MRI scan with radiolabel 68Ga-DOTA-TATE.
干预措施: Ga-68-DOTA-TATE (Drug)
68Ga-DOTA-TATE PET/MRI Scan
Participants will undergo a PET/MRI scan with radiolabel 68Ga-DOTA-TATE.
干预措施: Positron Emission Tomography / Magnetic Resonance Imaging (PET/MRI) Scan (Device)
结局指标
主要结局
Absolute Accuracy of SUV Max of PET/CT vs PET/MRI
时间窗: 4 hours
Standardized uptake value max (SUVmax) is a measurement of the maximum radiopharmaceutical uptake value within the region of interest (ROI). SUVmax is calculated as the ratio of activity concentration:injected dose/body weight. The outcome is reported as the mean SUVmax with standard deviation (SD), reported for 8 specific organs or bodily locations.
次要结局
- PET/CT vs PET/MRI Difference in Standardized Uptake Value Max (SUVmax), by Radiotracer(estimated average of 2 hours)
研究者
Andrei Iagaru
Associate Professor of Radiology
Stanford University