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临床试验/CTRI/2025/05/086613
CTRI/2025/05/086613尚未招募4 期

A Randomized Comparative Clinical Study of Local Application of Kutajadi Cream and Karveer Patra Cream in the Management of Garbhini Kikkis with special reference to Striae Gravidarum

Seth RV Ayurved Hospital1 个研究点 分布在 1 个国家目标入组 64 人开始时间: 2025年5月25日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
64
试验地点
1
主要终点
Size and Number of Striae lesion

研究概览

简要总结

Kikkis, also known as Striae Gravidarum, is the most common disorder that causes stretch marks to appear predominantly on the abdomen and thigh regions of pregnant women. In India, the prevalence rate of Striae Gravidarum is 80.78%, indicating poor skin elasticity among women.

Symptoms of Kikkis include severe Daha, Kandu, and Vaivarnya, which significantly affect the daily lives of women during pregnancy. Ancient texts by Acharya Charaka and Vagbhata explain the pathophysiology of Kikkis, stating that the growing fetus displaces all doshas in an upward direction, leading to the vitiation of these doshas. Vitiated vata dosha result in  Twak Vaivarnya (Skin Discolouration), due to Pitta dosha Daha (burning sensations) and Kandu (itching) due to Kapha dosha.

Ayurvedic treatments have been found to have minimal adverse effects, are cost-effective, and have been proven effective in treating dermatological disorders.

The Kutajadi cream contains the ingredients Kutaja, Arjaka beeja, Haridra, and Musta.

Kuataja having Kandughna,Vranaropak,Raktashodhan,Raktastambhak properties &having strong Astringent,Antiinflammetory action.

Arjaka beeja having Snehan,Dahaprashaman,Vranaropak,krimighna,Shothahar properties and shows Antioxident,Antiinflammatory,Antihistaminic action.

Musta is kandughna,Shothahar,Raktaprasadak & oils have analgesic and antiinflammetory action.

Haridra is Varnya, Kandughna, Kushthaghna, Vednasthapaka, Vranropak,Vranshodhaka,Raktawardhan properties & Analgesic,Antibacterial,antihistaminic,Anticeptic,Antioxident action.

Overall, Kutajadi cream combines properties that address itching (Kandughna), improve skin quality (Varnya), alleviate burning (Dahaprashamaka), relieve pain (Vedanashamak), and possess antihistaminic and anti-inflammatory effects, making it effective in reducing the symptoms of Kikkis.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Not Applicable

入排标准

年龄范围
20.00 Year(s) 至 40.00 Year(s)(—)
性别
Female

入选标准

  • Primigravida Patients Patients having symptoms of Kikkis in 2nd and 3rd trimester Pregnant Patients of age group 20-40years Voluntary Willing Patients Patients from all Socio-ecnomical class.

排除标准

  • Multipara Patients Multiple Pregnancy e.g. Twin pregnancy Pregnant Patients with other Skin Disesase or Skin Allergy Over Abdomen Patients having complications of pregnancy e.g. Polyhydromnios, PIH, Gestational Diabetes Patient having HIV, HbsAg, HCV, VDRL Positive.

结局指标

主要结局

Size and Number of Striae lesion

时间窗: 2 months

Daha- Burning sensation

时间窗: 2 months

Kandu- Itching

时间窗: 2 months

Vaivarnya- Discolouration

时间窗: 2 months

次要结局

未报告次要终点

研究者

发起方
Seth RV Ayurved Hospital
申办方类型
Other [Charitable Ayurvedic Hospital ]

研究点 (1)

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