CTRI/2018/11/016447Completed未知
Detection of Salivary IgA Anti CCP antibodies in patients with Rheumatoid Arthritis, and its correlation with serum IgG anti-CCP antibody level and disease activity
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Sponsor
- Maulana Azad Medical College
- Enrollment
- 111
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Observational
Eligibility Criteria
Inclusion Criteria
- •All adult patients with Rheumatoid Arthritis (RA), as defined by the 2010 ACR/EULAR classification criteria, will be eligible for the study. Healthy volunteers among the hospital staff will also be recruited to define normal salivary IgA Anti-CCP levels in healthy population. They will include volunteers with good orodental hygiene.
Exclusion Criteria
- •Exclusion criteria for Healthy Volunteers:
- •No first degree relatives with RA, no tobacco use and no past history of connective tissue disorders.
- •Exclusion criteria for RA patients:
- •Subjects with a history of smoking/current smokers/oral tobacco use
- •,with poor orodental hygiene,RA patients with coexisting connective tissue disorders like psoriatic arthritis ,Systemic Lupus Erythematosus (SLE),Primary Sjögrenâ??s Syndrome,with a history of pulmonary tuberculosis
Investigators
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