Comparison of dexmedetomidine and lidocaine infusion for postoperative analgesia in open cholecystectomy
Phase 2
Not yet recruiting
- Conditions
- Health Condition 1: K802- Calculus of gallbladder without cholecystitis
- Registration Number
- CTRI/2024/07/070420
- Lead Sponsor
- Dr Kamal Jyoti Kashyap
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
age 20-60 years ,American Society of Anaesthesiologists (ASA) grade I and II ,
posted for open cholecystectomy under general anaesthesia.
Exclusion Criteria
Allergy to study drugs , obesity (BMI more than 35), renal failure , liver failure , pregnancy, alcohol abuse , chronic use of analgesic or other drugs , decreased autonomic control ,malampatti grade III and IV
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie dexmedetomidine's analgesic effects in postoperative cholecystectomy patients with K80.2 gallbladder calculus?
How does lidocaine infusion compare to standard opioid-based analgesia for postoperative pain management in open cholecystectomy (K80.2)?
Which biomarkers correlate with improved analgesic response to alpha-2 adrenergic agonists like dexmedetomidine in abdominal surgery?
What are the potential adverse events of intravenous lidocaine versus dexmedetomidine in phase II postoperative analgesia trials?
Are there synergistic combinations of alpha-2 adrenergic agonists and local anesthetics being explored for enhanced postoperative pain control in gallbladder surgery?