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Clinical Trials/CTRI/2024/10/075788
CTRI/2024/10/075788
Completed
Phase 2

Effectiveness of Platelet-rich plasma and Low-level laser therapy in accelerating orthodontic tooth movement :A split mouth-Clinical study

Krishna Vishwa Vidhyapeeth School of dental sciences1 site in 1 country20 target enrollmentStarted: November 4, 2024Last updated:
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Overview

Phase
Phase 2
Status
Completed
Sponsor
Krishna Vishwa Vidhyapeeth School of dental sciences
Enrollment
20
Locations
1
Primary Endpoint
Accelerated tooth movement
OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Overview

Brief Summary

This is a split-mouth randomised clinical study; each sample receives platelet-rich plasma and low-level laser therapy on randomly assigned side of participants mouth as an intervention. Each group is under observation for a period of 3 months where the rate of orthodontic tooth movement is studied by taking impressions at a regular interval at start of canine retraction, 4th week and 8th week.

pain assessment and root resorption is also studied over a period of 3 months.

Study Design

Study Type
Interventional
Allocation
Coin toss, Lottery, toss of dice, shuffling cards etc
Masking
Participant Blinded

Eligibility Criteria

Ages
16.00 Year(s) to 25.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • •Patients having permanent dentition.
  • •Patients with Class 1 malocclusion with bimaxillary protrusion, Class II division I malocclusion, mild crowding in the range of 2-4 mm, and were indicated for maxillary first premolar extraction and bilaterally maxillary canine distalization.
  • •Age: Patients in the age group of 16-35 years of age.

Exclusion Criteria

  • •Patients with poor oral hygiene.
  • •Patients with impacted canines.
  • •Patients with recent major illness resulting in reduced platelet count.
  • •Patients on regular antibiotics, steroids, or anti-inflammatory drugs.

Outcomes

Primary Outcomes

Accelerated tooth movement

Time Frame: 3 months

Secondary Outcomes

  • Pain assessment(3 months)
  • root resorption of canine tooth(3 months)

Investigators

Sponsor
Krishna Vishwa Vidhyapeeth School of dental sciences
Sponsor Class
Private medical college
Responsible Party
Principal Investigator
Principal Investigator

Dr Harshali Zavar

School of Dental Sciences Krishna Institute of Medical Sciences Maharashtra

Study Sites (1)

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