Correlation of Serum Lactate and Activity of Multiple Sclerosis

• Conditions: Multiple Sclerosis
• Interventions: Radiation: Magentic resonanace imaging; Radiation: Magentic resonanace spectroscopy

• Registration Number: NCT04210960
• Lead Sponsor: Mansoura University Hospital

Brief Summary

Correlation of serum lactate and activity of multiple sclerosis and its correlation to different type of MS

Detailed Description

Correlation of serum lactate and activity of multiple sclerosis and its correlation to different type of MS and magentic resonanace imaging , magentic resonanace spectroscopy

Study Timeline

• Status Verified: 2019-12
• Study First Submitted: 2019-12-22
• Study First Submitted QC: 2019-12-22
• Study Start: 2019-12-23
• Last Update Submitted: 2019-12-24
• Study First Posted: 2019-12-26
• Last Update Posted: 2019-12-27
• Primary Completion: 2020-05-01
• Study Completion: 2020-06-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

-Patients with multiple sclerosis (RRMS,PPMS and SPMS)

Exclusion Criteria

-Patients with any other medical conditions that may affect the serum lactate level

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients group	Magentic resonanace imaging	50 multiple sclerosis patients
Control group	Magentic resonanace imaging	30 normal healthy control
Control group	Magentic resonanace spectroscopy	30 normal healthy control
Patients group	Magentic resonanace spectroscopy	50 multiple sclerosis patients

Primary Outcome Measures

Name	Time	Method
Biochemical testing	2 days	Plasma lactate was assayed according to Trinder method14 . All assays were carried out with Bechman Coulter AU480 autoanalyzer (USA).

Trial Locations

Locations (1)

Mansoura University Hospital; 🇪🇬 Mansoura, Dakahlia, Egypt