Studying cough in people with swallowing difficulties after stroke.

Not yet recruiting

Conditions: Stroke with Dysphagia adults.

Registration Number: CTRI/2017/10/010180

Lead Sponsor: Kasturba Medical College

Brief Summary: Dysphagia is closely associated with stroke, andaspiration pneumonia is a main cause of death among stroke patients (Perry L,et al., 2001; Hinchey J. A, et al., 2005). Dysphagia and relatedcomplications increase length of acute stay and are associated with increasedmortality, comorbidity, and increased health care costs (Smithard et al.,1997).In many neurogenic populations, dystussia (impaired cough) anddysphagia are present in parallel (Mann et al,2000; Vellas et al ,2000), afinding that is not surprising given the shared neural and anatomicalsubstrates of respiration, cough and swallowing function (Gestreauet,al 1996;Pitts T et,al 2012; Troche et al, 2014).

An effective cough is critical in removing aspirated material from theairway during swallowing, particularly in patients with additionalco-morbidities who are more susceptible to developing pulmonary sequelae. Howeveroff late the cough testing in the clinical swallowing evaluation has also been a recent topic of interestto provide information regarding mechanisms of airway safety and the physiologicability of an individual to defend their airway (Smith Hammond CA, et al. 2001;Pitts T, et al.2008; Plowman EK, et al. 2016).

Currently,however, cough testing is not routinely incorporated in the CSE across all settings,although there are several investigations probed into the cough, its differenttypes, aerodynamic analysis of cough.

This study aims to investigate the coughusing acoustic analysis in individuals with dysphagia.

A total of 30 participants will be recruited for the study and cough sample will be recorded before and after swallow with an Olympus Linear Pcm LS-P2 Voice Recorder placed approximately 10cm from the participantâ€™smouth using the PRAAT software installed in the laptop. The participant will be instructed to cough voluntarilyon three trials. The best cough sample will be used for both perceptual andacoustic analysis.

Cough will be analysed perceptually on arating scale. Objectively thecough samples will be analysed by computing theMel-Frequency Cepstral Coefficients (MFCC) and its derivatives with the help ofMATLAB tool.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 30

Inclusion Criteria

Individuals with acute post stroke (Brain stem and Non Brain stem lesions) 2.
Adults in the age range of 41-60 years (Eriksonâ€™s stages of psychosocial development, 1968).
Individuals who are on tube dependent for feed.

Exclusion Criteria

Tracheostomy/ Ventilator/ GCS less than 8 2.
Neurodegenerative disorder, Gastrointestinal disorders 3.
Unable to follow instructions (Aphasia/ Cognitive problems/ Hearing loss).

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
OBJECTIVES:	6 months
Aim: To investigate the cough using acoustic analysis in individuals with dysphagia	6 months
To compare cough between pre and post swallow acoustically	6 months
To compare cough between pre and post swallow perceptually	6 months

Secondary Outcome Measures

Name	Time	Method
Aim: To investigate the cough using acoustic analysis in individuals with dysphagia	OBJECTIVES:

Trial Locations

Locations (1): Kasturba Medical College
🇮🇳
Udupi, KARNATAKA, India
Kasturba Medical College
🇮🇳Udupi, KARNATAKA, India
Carol Melanie Alvares
Principal investigator
9964978491
carol_alvares@yahoo.com