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Phase I/II trial of oral hydroxyurea in combination with pegylated interferon and ribavirin in chronic hepatitis C patients

Phase 1
Conditions
Chronic hepatitis C
Registration Number
JPRN-UMIN000003457
Lead Sponsor
Yokohama City University Medical Center Gastroenterological Center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
20
Inclusion Criteria

Not provided

Exclusion Criteria

1)Pregnant or lactating Women 2)Patients with uncontrolled heart disease 3)Patients with uncontorolled DM or HT 4)Patients with inadequate haematological status 5) Patients with exclusion criteria for PEG/RBV therapy 6) Patient with decision of exclusion

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
PhaseI:The safety PhseII:Antiviral effect
Secondary Outcome Measures
NameTimeMethod
PhaseI:Antiviral effect PhaseII: The safety, ALT change
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