Comparison of the effect of Hypericum perforutum Vaginal gel and Clotrimazole Vaginal cream on Vaginal Candida albicans infection: A double-blind randomized clinical trial

Phase 3

Recruiting

• Conditions: Candida vaginitis.; Subacute and chronic vaginitis; N76.1

• Registration Number: IRCT20231017059753N1
• Lead Sponsor: Yasouj University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

1- Women of reproductive age (18-49)-
2- Presence of cheesy vaginal discharge and doctor's confirmation
3- Complaints of burning, itching and swelling and pain in the vulva and vagina
4- Absence of other vaginal infections
5- Willingness to participate in the study
6- Women with sexual partners

Exclusion Criteria

1- Lactating women
2- Pregnant women
3- Women who smoke
4- The possibility of starting menstruation in the next 10 days
5- Having abnormal vaginal bleeding at the time of sampling
6- Having intercourse in the last 24 hours
7- Washing the vagina and using vaginal medicine in the last 48 hours
8- Having a history of any type of transplantation and using immunosuppressive drugs and broad-spectrum antibiotics, hormonal drugs and combined contraceptive pills, anti prostaglandins and anticoagulant drugs in the last month, and antiepileptic and migraine drugs or women with Heart and kidney diseases or sexually transmitted diseases.
9- History of Candida infection in the last 6 months and its treatment
10- History of candidal vaginitis

Study & Design

• Study Type: interventional
• Study Design: Not specified