Evaluation of the effects of general anesthesia and ultrasonography-guided interscalene block on pain and oxidative stress using thiolâ€disulfide balance and C-reactive protein levels: a randomized trial
- Conditions
- Patients undergoing shoulder surgeryArthroscopyBrachial plexus blockC-Reactive proteinGeneral anesthesiaPainSulfhydril compounds.
- Registration Number
- TCTR20200329001
- Lead Sponsor
- none
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 42
patients scheduled to undergo shoulder arthroscopy were those who presented to the Orthopedics and Traumatology Outpatient Clinics of our hospital with a complaint of shoulder pain and who remained unresponsive to conservative therapies after being diagnosed with subacromial impingement syndrome.
; those allergic to the medications used in the present study; those who were obese (body mass index [BMI] > 35 kg/m2); those with an infection at the injection site; those who underwent surgical intervention or had anatomical deformation at the relevant site; those receiving antithrombotic therapy and thus having changes in coagulation parameters; those with severe pulmonary disease, phrenic nerve palsy, diaphragm paralysis, pneumothorax, or neurological dysfunction in upper extremities; those who have received or are currently receiving psychiatric therapy; those receiving opioid therapy for a long period; those with known alcohol and/or drug addiction; those with diabetes mellitus, rheumatoid arthritis, chronic kidney failure, liver diseases, cardiac insufficiency, or Alzheimer’s disease; oncology patients; those who did not accept the relevant anesthesia method after randomization; and those with pathologies such as labral lesions, recurrent instability, or rotator cuff rupture requiring arthroscopic procedure in addition to subacromial decompression
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method oxidative stress intreoperative and postoperative 18 hours thiolâ€disulfide balance and C-reactive protein
- Secondary Outcome Measures
Name Time Method pain in postoperative 18 hours visual analgue scale