CTRI/2020/01/022685招募中不适用
A comparative study between oral clonidine and oral pregabalin on perioperative haemodynamic response and post operative analgesia in patients undergoing laparoscopic cholecystectomy under general anaesthesia
JLN Medical college and hospital Ajmer1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2020年11月1日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Haemodynamic changes
研究概览
简要总结
Theaim of this study is to compare and evaluate the efficacy of two different drugoral clonidine and oral pregabalin in perioperative haemodynamic response tolaryngoscopy, endotracheal intubation, pneumoperitonium and post operativeanalgesia and sedation with respect to-
PRIMARY OBJECTIVE-
- Haemodynamic changes
SECONDARY OBJECTIVES-
1. Postoperative analgesia
2. Levelof Sedation
- Any significant side effects or complications
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult patients of ASA grade I and II aged between 18 and 60 years of either sex posted for laparoscopic cholecystectomy surgery under general anaesthesia.
排除标准
- •ASA grade III and above.
- •Age <18 years & > 60 years.
- •Patients with severe systemic disease like IDDM, uncontrolled hypertension, kidney and liver disease, severe respiratory disease.
- •Seizure disorder.
- •Coronary artery disease or recent history of MI.
- •Anticipated difficult intubation.
- •Body weight>100 kg or obese.
- •Pregnant and lactating women.
- •Mentally impaired patients.
- •Patients of psychiatric disorders and sleep disorders.
- •Patients on steroids since last 6 months.
- •Hypersensitivity to study drugs.
结局指标
主要结局
Haemodynamic changes
时间窗: 1 year
次要结局
- Post operative analgesia(Level of Sedation)
研究者
研究点 (1)
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