Comparison between oral clonidine and oral pregabalin tablet on vitals during operation and pain duration after laproscopic gall bladder operation

Recruiting

• Conditions: Calculus of gallbladder with othercholecystitis,

• Registration Number: CTRI/2020/01/022685
• Lead Sponsor: JLN Medical college and hospital Ajmer

Brief Summary

Theaim of this study is to compare and evaluate the efficacy of two different drugoral clonidine and oral pregabalin in perioperative haemodynamic response tolaryngoscopy, endotracheal intubation, pneumoperitonium and post operativeanalgesia and sedation with respect to-

PRIMARY OBJECTIVE-

1. Haemodynamic changes

SECONDARY OBJECTIVES-

1. Postoperative analgesia

2. Levelof Sedation

3. Any significant side effects or complications

Detailed Description

Not available

Study Timeline

• Study Start: 2020-11-01
• Last Update Posted: 2021-08-04

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Adult patients of ASA grade I and II aged between 18 and 60 years of either sex posted for laparoscopic cholecystectomy surgery under general anaesthesia.

Exclusion Criteria

• ASA grade III and above.
• Age <18 years & > 60 years.
• Patients with severe systemic disease like IDDM, uncontrolled hypertension, kidney and liver disease, severe respiratory disease.
• Seizure disorder.
• Coronary artery disease or recent history of MI.
• Anticipated difficult intubation.
• Body weight>100 kg or obese.
• Pregnant and lactating women.
• Mentally impaired patients.
• Patients of psychiatric disorders and sleep disorders.
• Patients on steroids since last 6 months.
• Hypersensitivity to study drugs.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Haemodynamic changes	1 year

Secondary Outcome Measures

Name	Time	Method
Post operative analgesia	Level of Sedation

Trial Locations

Locations (1)

J.L.N. Medical college; 🇮🇳 Ajmer, RAJASTHAN, India

J.L.N. Medical college

🇮🇳Ajmer, RAJASTHAN, India

Rajendrapal singh rathore

Principal investigator

9672140069

drrajendrapalsingh0952@gmail.com