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临床试验/NL-OMON48639
NL-OMON48639已完成不适用

The pathophysiology of post-extubation dysphagia in ICU patients - Post-extubation dysphagia

Radboud Universitair Medisch Centrum0 个研究点目标入组 30 人开始时间: 待定最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
30

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 64(—)

入选标准

  • Age >= 18 years
  • Informed consent
  • Extubated after endotracheal intubation for more than 5 days (> 5 days)
  • Between RASS -2 and +2
  • Able to sit right up
  • No respiratory insufficiency/failure (for this study defined as a SpO2 < 92%
  • with a minimum of 3 L nasal oxygen).
  • Inclusion criteria of the group of healthy persons:
  • Age >= 18 years
  • Informed consent

排除标准

  • Pre-existing dysphagia
  • Tracheostomy or previous tracheostomy
  • History of prior intubation < 3 months ago
  • Head/neck surgery, head/neck radiation or head/neck disease
  • Pre-existent esophageal disorder
  • Coagulopathy (thrombocytes < 50*10^9 /l, or PT/APTT > 1.5 times the reference
  • value, or fibrinogen < 1000 mg/l, or use of therapeutic anticoagulation drugs)
  • Allergy for xylometazoline (only if indicated)
  • Allergy for methylene blue
  • Known pregnancy
  • Known G6PD deficiency

研究者

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