Myoclonus after Cardiopulmonary Resuscitatio

Withdrawn

• Conditions: involuntary muscle contractions; Muscle jerks; 10039911

• Registration Number: NL-OMON37677
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

Admission after CPR (cardiac or hypoxic arrest)
Acute posthypoxic myoclonus within 72 hours after admission

Exclusion Criteria

Age < 18 years
Presence of myoclonus before CPR
Traumatic cause of CPR (hypovolemic arrest)
Severe traumatic brain injury
Medical history of epilepsy / Epilepsy syndromes in which myoclonus is prominent and in which patients can develop myoclonus status epilepticus such as juvenile myoclonic epilepsy and progressive myoclonic epilepsies
Possible explanations for seizures or myoclonus other than the anoxic-ischemic event
Generalized tonic-clonic seizure(s) as cause of the myoclonus
Drug overdose

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Intraclass correlation coefficient in assessing acute posthypoxic myoclonus in<br /><br>patients after cardiopulmonary resuscitation. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Investigate characteristics of clinical neurophysiological investigations<br /><br>(electroencephalography (EEG) and somatosensory evoked potentials (SEP)) in<br /><br>patients with acute posthypoxic myoclonus after cardiopulmonary resuscitation. </p><br>