Preoperative Serum Albumin and Duration of Intraoperative Hypotension on Postoperative Acute Kidney Injury

Completed

• Conditions: Acute Kidney Injury

• Registration Number: NCT03882658
• Lead Sponsor: Peking University First Hospital

Brief Summary

Acute kidney injury is one of major adverse postoperative complications. research about postoperative acute kidney injury conclude that low preoperative albumin and intraoperative hypotension is associated to postoperative acute kidney injury. However, due to ethic issue and nonlinear realtionship between these factors and postoperative acute kidney injury, the exact threshold of these two risk factors were not be able to identified. The research tried to locate the exact threshold with implementation of penalized splines by generalized additive model.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-10
• Primary Completion: 2019-01-20
• Study Completion: 2019-02-15
• Study First Submitted: 2019-03-18
• Study First Submitted QC: 2019-03-18
• Study First Posted: 2019-03-20
• Status Verified: 2019-05
• Last Update Submitted: 2019-05-04
• Last Update Posted: 2019-05-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 37610

Inclusion Criteria

adult non-cardiac, non-obsteric, non- kidney elective surgery patients

Exclusion Criteria

patients aged <18 y emergency surgeries without arterial blood pressure cardiac surgeries obstetric surgeries kidney surgeries under local infiltration or MAC first SBP <100 mmHg

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
incidence and odds ratio of postoperative acute kidney injury	30 days postoperatively in hospital	incidence and odds ratio of postoperative acute kidney injury

Trial Locations

Locations (1)

First hospital Peking University; 🇨🇳 Beijing, Beijing, China