Preoperative Serum Albumin and Duration of Intraoperative Hypotension on Postoperative Acute Kidney Injury: a Retrospective Cohort Analysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 37,610
- 试验地点
- 1
- 主要终点
- incidence and odds ratio of postoperative acute kidney injury
研究概览
简要总结
Acute kidney injury is one of major adverse postoperative complications. research about postoperative acute kidney injury conclude that low preoperative albumin and intraoperative hypotension is associated to postoperative acute kidney injury. However, due to ethic issue and nonlinear realtionship between these factors and postoperative acute kidney injury, the exact threshold of these two risk factors were not be able to identified. The research tried to locate the exact threshold with implementation of penalized splines by generalized additive model.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult non-cardiac, non-obsteric, non- kidney elective surgery patients
排除标准
- •patients aged <18 y emergency surgeries without arterial blood pressure cardiac surgeries obstetric surgeries kidney surgeries under local infiltration or MAC first SBP <100 mmHg
结局指标
主要结局
incidence and odds ratio of postoperative acute kidney injury
时间窗: 30 days postoperatively in hospital
incidence and odds ratio of postoperative acute kidney injury
次要结局
未报告次要终点
研究者
Yan Zhou, MD
Principal Investigator
Peking University First Hospital