Evaluation of Postoperative Kidney Functions in Geriatric Patients Undergoing Major Gynecologic-Oncologic Surgery: A Retroceptive - Cohort Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Geriatrics
- Sponsor
- Ankara City Hospital Bilkent
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- the incidence of the patients with AKI stage 2
- Last Updated
- 4 years ago
Overview
Brief Summary
The increasing number of patients who develop perioperative acute kidney injury (AKI) is partly related to the aging population and the increasing number of individuals with chronic comorbidities, particularly those with premorbid chronic kidney disease. Anesthesiologists and surgeons will increasingly have to deal with such patients who are elderly and have comorbidities and require major surgery.
The aim of this study was to determine the incidence of postoperative acute kidney injury (primary aim) in patients aged 65 and over who underwent elective major gynecological-oncological surgery under general anesthesia in Ankara City Hospital Gynecology-Oncology Operating Room between January 2020-2022 and were followed up in the PACU in the postoperative period. To investigate risk factors and their results in a retrospective manner in line with the KDIGO criteria (secondary purpose).
Investigators
aysun postaci
Principal İnvestigator
Ankara City Hospital Bilkent
Eligibility Criteria
Inclusion Criteria
- •patients underwent major abdominal gynecologic oncologic surgery between January 2021 and January 2022
- •followed in the PACU
Exclusion Criteria
- •Patients with inaccessible data and missing data
Outcomes
Primary Outcomes
the incidence of the patients with AKI stage 2
Time Frame: 48 hours after surgery
AKI STAGE 1 : increase Cr ≥ 0.3 mg/dl or increase Cr to 1.5-1.9 times from baseline; or urine volume \< 0.5 ml/kg/h for 6-12 hours AKI STAGE 2 : increase to 2-2.9 times from baseline; or urine volume \< 0.5 ml/kg/h for ≥ 12 hours AKI STAGE 3 : increase Cr to ≥ 3 times from baseline; or increase Cr ≥ 4 mg/dl or initiation of renal replacement therapy or decrease in GFR to \<35mL/min/1.73 m2 or urine volume \< 0.3 ml/kg/h for ≥ 24 hours or Anuria for ≥ 12 hours
the incidence of the patients with AKI stage 3
Time Frame: 48 hours after surgery
AKI STAGE 1 : increase Cr ≥ 0.3 mg/dl or increase Cr to 1.5-1.9 times from baseline; or urine volume \< 0.5 ml/kg/h for 6-12 hours AKI STAGE 2 : increase to 2-2.9 times from baseline; or urine volume \< 0.5 ml/kg/h for ≥ 12 hours AKI STAGE 3 : increase Cr to ≥ 3 times from baseline; or increase Cr ≥ 4 mg/dl or initiation of renal replacement therapy or decrease in GFR to \<35mL/min/1.73 m2 or urine volume \< 0.3 ml/kg/h for ≥ 24 hours or Anuria for ≥ 12 hours
the incidence of the patients with AKI STAGE 1
Time Frame: 48 hours after surgery
AKI STAGE 1 : increase Cr ≥ 0.3 mg/dl or increase Cr to 1.5-1.9 times from baseline; or urine volume \< 0.5 ml/kg/h for 6-12 hours AKI STAGE 2 : increase to 2-2.9 times from baseline; or urine volume \< 0.5 ml/kg/h for ≥ 12 hours AKI STAGE 3 : increase Cr to ≥ 3 times from baseline; or increase Cr ≥ 4 mg/dl or initiation of renal replacement therapy or decrease in GFR to \<35mL/min/1.73 m2 or urine volume \< 0.3 ml/kg/h for ≥ 24 hours or Anuria for ≥ 12 hours