Limitations of Using a Sheimpflug Image-Based Device for Measuring Anterior Chamber Depth in Pseudophakic Eyes

Completed

• Conditions: Cataract

• Registration Number: NCT00712231
• Lead Sponsor: Far Eastern Memorial Hospital

Brief Summary

There have been numerous studies comparing various ACD measurements in phakic eyes,while researches comparing ACD in pseudophakic eyes are less extensive. With the recent popularity of presbyopia correction, measuring the ACD will facilitate differentiating pseudophakic accommodation from pseudoaccommodation. It is thus mandatory to verify the accuracy of ACD measurement of these devices since the innovation of various IOLs in the recent decade makes this task more complicated. In this study, we will assess the limitations of using Pentacam for ACD measurement in pseudophakic eyes and compare Pentacam measurement with IOLMaster and A-scan measurements.

Detailed Description

In this prospective study, ACD was measured in 90 phakic and 94 pseudophakic eyes by Pentacam, IOLMaster and A-scan. Correlations and differences between the three measurements were investigated. The accuracy in detecting the anterior lens surface in pseudophakic eyes was also assessed.Differences in ACD-Pen, ACD-IOLM, and ACD-A were analyzed using one-way analysis of variance (ANOVA). When an overall significance of P\< 0.05 was obtained, pair-wise comparisons were made using Tukey's multiple comparison t tests. The association between ACD-Pen, ACD-IOLM, and ACD-A was assessed using Pearson's correlation test. The distribution of erroneous ACD-Pen measurement for the three IOLs was analyzed with the chi-square test. In all analyses, P \<0.05 was considered statistically significant.

Study Timeline

• Study Start: 2008-01
• Primary Completion: 2008-02
• Study Completion: 2008-02
• Status Verified: 2008-07
• Study First Submitted: 2008-07-07
• Study First Submitted QC: 2008-07-08
• Last Update Submitted: 2008-07-08
• Study First Posted: 2008-07-09
• Last Update Posted: 2008-07-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 184

Inclusion Criteria

• Phakic group: randomized
• Pseudophakic eyes : the cases accepted cataract surgery

Exclusion Criteria

• Previous ocular trauma or intraocular surgery other than cataract surgery;

• Contact lens use in the past two months;

• Use of medication that might affect the pupil; corneal disease or ocular infection;

• History of ocular disease, such as

  • Dry eye syndrome
  • Uveitis
  • Glaucoma
  • Ocular tumor

• Cases with any surgical complications were also excluded.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified