Effect of periodontal treatment on blood vessels and inflammation in type 2 diabetics with gum disease

Not Applicable

Recruiting

• Conditions: C18.452.394.750.149; C07.465.714.533; Type 2 diabetes mellitus, severe periodontitis

• Registration Number: RBR-69yzkb
• Lead Sponsor: Hospital Universitário Pedro Ernesto

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-02-19
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients with severe periodontitis; both genders; more than 18 years old; at least 12 teeth; type 2 diabetes mellitus

Exclusion Criteria

HIV; immunological and chronic inflammatory diseases; prolonged usage of medications 6 months before the start of the study as antibiotics; cortisone; antihistamine; hormones; and others

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean differences in endothelial and microvascular functions evaluated by videocapillaroscopy and pletismography pre and post intervention

Secondary Outcome Measures

Name	Time	Method
Differences in gingival fluid and blood levels of immunoinflammatory biomarkers evaluated by multiplex pre and post intervention