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临床试验/CTRI/2014/04/004552
CTRI/2014/04/004552已完成3 期

À clinical study of agnikarma and panchatikta guggulu in the management of sandhivata w.s.r to osteoarthritis of knee joint

Post graduate teaching hospital1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2013年3月23日最近更新:

试验速览

阶段
3 期
状态
已完成
发起方
入组人数
30
试验地点
1
主要终点
Betterment in Vedana Pain

研究概览

简要总结

Osteoarthritis is the commonest form of joint disease and very painful disabling in advancing years. Patients of osteoarthritis need to take analgesics for daily and lifelong. In O A surgery knee joint replacement is very costly and patient has to continue analgesics for long duration. These analgesics and steroids in old age produce averse effects like gastritis hyperacidity renal failure etc. Agnikarma (therapeutic application of heat) which is a non pharmacological treatment relieves the clinical features of the condition without the use of analgesics for longer duration. The combined treatment modality of para surgical and oral medication is tried to assess  the efficacy of agnikarma (theurapeutic heat) in one group and Agnikarma with panchatiktaka ghritha guggulu (ayurved medicated formulation) in another group. The agnikarma was done with a special panchadhatu Shalaka (metal rod designed with of five metals like Copper- 40%, Iron- 30%,  Zinc- 10%, Silver- 10% and Tin       -10% ). Agnikarma was done at medial and lateral site of affected knee joint. Total 15 bindu dagdha (dot like points were made with red hot metal rod) at every time for four times in a month. Agnikarma was done by weekly interval in four sitting in both groups. Assessment of relief in sign and symptoms was done after every seven days upto one month and followed up for one month. After completion of study  encouraging result  was observed in symptomatic relief. The re was complete pain relief in more than 80% patients after completion of treatment. ROM was improved in 50% of patients. In x-ray finding there was no change after completion of treatment as that was the structural defect. Finally study concluded that there is symptomatic relief with Agnikarma procedure in cases of OA knee joint.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Open Label

入排标准

年龄范围
45.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Patients suffering from Janugata Sandhivata(O A of Knee joint) Patients between age group 45-70years of both sex.

排除标准

  • 1 Age below 45 years and above 70 years 2 Patients of Diabetes Mellitus Rheumatoid arthritis Knee joint effusion 3 Other diseases like Paralysis Parkinson s Disease Severe anaemia and malignancy 4 Secondary joint pain due to Tuberculosis AIDS Leprosy.

结局指标

主要结局

Betterment in Vedana Pain

时间窗: among 4 sittings every week patient will be assessed, and in the follow up period of 4 weeks also every week we will assess patient

Stambha Stiffness and Vata purna drutisparsha Crepitus will be assessed subjectively

时间窗: among 4 sittings every week patient will be assessed, and in the follow up period of 4 weeks also every week we will assess patient

Gonometric measurement of flexion and extension of knee joint

时间窗: among 4 sittings every week patient will be assessed, and in the follow up period of 4 weeks also every week we will assess patient

Shotha Swelling

时间窗: among 4 sittings every week patient will be assessed, and in the follow up period of 4 weeks also every week we will assess patient

次要结局

  • Change in X ray Knee joint(Efficacy and saftey)

研究者

发起方
Post graduate teaching hospital
申办方类型
Research institution and hospital

研究点 (1)

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