Effects of Different Endurance Training Protocols on Physical Performance in Cardiac Patients
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Individual maximum power output in watt (Pmax)
研究概览
简要总结
It is the aim of the study to compare the effects of 6 weeks of either high-intensity interval training (HIT; carried out at correctly assessed 85-95% of maximal heart rate), pyramid, or continuous endurance training, on changes of physical exercise capacity in cardiac patients.
The three exercise arms (isocaloric) are composed as follows:
Endurance training (n=15): 31min at 65-75% HRmax; HIT (n=15): 4x4min intervals at 85-95% HRmax divided by 3x3min of active recovery at 60-70% HRmax, making it a total of 25min; Pyramids (n=15): One Pyramid consists of 8 one-minute blocks. Those are grouped starting with one block of 70-75% HRmax, followed by one block at 75-80% HRmax and another one at 80-85% HRmax. The top of the pyramid are 2 blocks of 85-90% HRmax. Intensity is lowered afterwards with one block at 80-85% HRmax, followed by one block at 75-80% HRmax and last one at 70-75% HRmax. Two more pyramids follow, each divided by 2min of active recovery at 65-70% HRmax, making it a total of 28min.
All protocols are initiated by 5min of warm-up and end with 5min of cool-down, both at 60-70% HRpeak.
Primary Outcome: Individual maximum power output in watt (Pmax). Secondary Outcome: Change of power output in watt at lactate thresholds at 2 and 4 mmol/l.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 25 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •At least one of the following diagnoses within the previous 3 months:
- •acute coronary syndrome (STEMI)
- •acute coronary syndrome (NSTEMI)
- •aortocoronary bypass surgery
- •stable coronary heart disease
排除标准
- •Unstable angina pectoris
- •Heart failure (NYHA IV)
- •Acute endomyocarditis or other acute infections
- •Pulmonary artery embolism or phlebothrombosis within the previous 6 months
- •Hemodynamically unstable arrhythmia
- •Hypertrophic cardiomyopathy
- •participation in another study within the previous 6 months
- •Medical conditions which prevent patients from complying with the exercise program
结局指标
主要结局
Individual maximum power output in watt (Pmax)
时间窗: 6 weeks
Change of individual maximum power output in watt (Pmax) on a bicycle ergometer after the training intervention of controlled physical activity within 6 weeks
次要结局
- Power output in watt at lactate threshold of 2 and 4 mmol/l(6 weeks)
研究者
Prof. Josef Niebauer M.D., Ph.D., MBA
Primar
Paracelsus Medical University