In vivo quantification of the cerebral monoacylglycerol lipase using [18F]T-401
Not Applicable
- Conditions
- ormal healthy controls
- Registration Number
- JPRN-UMIN000031787
- Lead Sponsor
- Department of Functional Brain Imaging Research National Institute of Radiological Sciences National Institutes for Quantum and Radiological Science and Technology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Male
- Target Recruitment
- 13
Inclusion Criteria
Not provided
Exclusion Criteria
1. Subjects who do not have ability to make informed consent. 2. Subjects with any psychiatric disorder or subjects with severe physical complication 3. Subjects who currently smokes 4. Subjects with any organic brain disorder 5. Subjects with metallic medical device in the body 6. Subjects with tattoo 7. Subjects with severe claustrophobia 8. Subjects with a history of allergy to heparin and local anesthetics. 9. Subjects who has participated in other study in recent 6 months 10. Subjects who has participated in blood donation in recent 12 weeks 11. Subjects who is considered to be inappropriate to participate in the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pharmacokinetics and distribution volume of[18F]T-401 in human brain. Effective dose of [18F]T-401 in human
- Secondary Outcome Measures
Name Time Method Relationship between the density of MAGL and cognitive function